Neighborhood Environment and Stress: Findings from the ESSE-RF-3 Epidemiological Study

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Marina B. Kotova, Sergey A. Maksimov, Svetlana A. Shalnova, Yulia A. Balanova, Asiia E. Imaeva, Vladimir A. Kutsenko, Galina A. Muromtseva, Svetlana E. Evstifeeva, Anna V. Kapustina, Natalia S. Karamnova, Olga B. Shvabskaya, Tatyana V. Repkina, Tatyana O. Gonoshilova, Alexander V. Kudryavtsev, Natalia I. Belova, Leonid L. Shagrov, Marina A. Samotrueva, Anna L. Yasenyavskaya, Olga A. Bashkina, Svetlana V. Glukhovskaya, Irina A. Levina, Ekaterina A. Shirshova, Etta B. Dorzhieva, Ekaterina Z. Urbanova, Natalia Yu. Borovkova, Vladimir K. Kurashin, Anastasia S. Tokareva, Yulia I. Ragino, Galina I. Simonova, Alyona D. Khudyakova, Vadim N. Nikulin, Oleg R. Aslyamov, Galina V. Khokhlova, Alla V. Solovieva, Andrey A. Rodionov, Olga V. Kryachkova, Yulia Yu. Shamurova, Evgeny V. Mikhailov, Yulia O. Tarabrina, Magomedrasul G. Ataev, Magomed O. Radzhabov, Zulmira M. Gasanova, Murat A. Umetov, Inara A. Hakuasheva, Lilia V. Elgarova, Ekaterina I. Yamashkina, Larisa A. Balykova, Anna A. Usanova, Alyona M. Nikitina, Nadezhda V. Savvina, Yulia E. Spiridonova, Elena A. Naumova, Daria A. Kashtanova, Vladimir S. Yudin, Anton A. Keskinov, Sergey M. Yudin, Anna V. Kontsevaya, Oxana M. Drapkina
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e0309
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Abstract: 
Introduction — Both Russian and international studies demonstrate that living environment and neighborhood characteristics have influence on health status, including mental well-being. The aim of the study was to examine the associations between neighborhood environment and individual likelihood of stress among the Russian population. Material and Methods — The multicentre study “Epidemiology of Cardiovascular Diseases and Their Risk Factors in the Regions of the Russian Federation. Third Survey” was conducted in 2020-2022 across 15 regions of Russia. The analysis included 28,731 men and women aged 35-74 years. Neighborhood infrastructure was assessed using the Russian version of the NEWS questionnaire, while stress was measured with the Perceived Stress Scale (PSS; Cohen’s Scale). Associations between stress and neighborhood infrastructure characteristics were evaluated using logistic regression adjusted for covariates. Results were presented as odds ratios (OR) with 95% confidence intervals (CI). Results — A lower likelihood of stress was associated with shorter distances from the place of residence to facilities (OR=0.91; 95% CI 0.87-0.94), greater accessibility of key facilities (OR=0.51; 95% CI 0.48-0.55), and improved traffic-related safety (OR=0.60; 95% CI 0.56-0.66). In contrast, higher population density (OR=1.002; 95% CI 1.001-1.004), better pedestrian infrastructure quality (OR=1.16; 95% CI 1.10-1.22), and enhanced neighborhood aesthetics (OR=1.08; 95% CI 1.03-1.13) were associated with increased stress probability. Conclusion — The results of the study showed a substantial impact of certain neighborhood characteristics on stress, an indicator of mental health in the Russian population. The link between residential environment and mental health can be applicable in public health, policy-making, and urban planning.
Cite as: 
Kotova MB, Maksimov SA, Shalnova SA, Balanova YuA, Imaeva AE, Kutsenko VA, Muromtseva GA, Evstifeeva SE, Kapustina AV, Karamnova NS, Shvabskaya OB, Repkina TV, Gonoshilova TO, Kudryavtsev AV, Belova NI, Shagrov LL, Samotrueva MA, Yasenyavskaya AL, Bashkina OA, Glukhovskaya SV, Levina IA, Shirshova EA, Dorzhieva EB, Urbanova EZ, Borovkova NYu, Kurashin VK, Tokareva AS, Ragino YuI, Simonova GI, Khudyakova AD, Nikulin VN, Aslyamov OR, Khokhlova GV, Solovieva AV, Rodionov AA, Kryachkova OV, Shamurova YuYu, Mikhailov EV, Tarabrina YuO, Ataev MG, Radzhabov MO, Gasanova ZM, Umetov MA, Hakuasheva IA, Elgarova LV, Yamashkina EI, Balykova LA, Usanova AA, Nikitina AM, Savvina NV, Spiridonova YuE, Naumova EA, Kashtanova DA, Yudin VS, Keskinov AA, Yudin SM, Kontsevaya AV, Drapkina OM. Neighborhood environment and stress: Findings from the ESSE-RF-3 Epidemiological Study. Russian Open Medical Journal 2025; 14: e0309.
DOI: 
10.15275/rusomj.2025.0309

Introduction

A significant number of Russian and international studies shows that human health depends on the environment, including territorial characteristics of the area of residence [1, 2]. A residential neighborhood is an artificially created environment characterized by well-designed land use and transportation networks, improved public and courtyard spaces, thoughtfully planned building density, favorable social and utility infrastructure, and an aesthetically appealing natural and territorial landscape [3]. Since individuals spend a considerable time within their neighborhood, its influence is highly significant. Accordingly, the link between neighborhood characteristics and health outcomes has been attracting increasing attention from researchers and public health administrators [4].

Living in favorable conditions is associated with better physical health, lower prevalence of chronic diseases, and reduced mortality rates [5]. These associations can be explained by broader opportunities for education, employment, recreation, access to well-developed social infrastructure, and a wider range of services, including health care [6]. Neighborhood characteristics and the way they are perceived may influence not only physical health but also certain aspects of mental health, such as stress, depression, anxiety, and overall life satisfaction [7]. Over the past two decades, interest in the role of the “place of residence” in shaping population mental health has increased substantially [8]. In fact, this research problem has evolved into a new interdisciplinary field within health geography, integrating perspectives from ecology, public health, psychology, urban and rural planning, as well as sociology [9, 10].

According to Stanislav Kasl, stress may be associated with individual characteristics, as well as with neighborhood environmental factors [11]. Living in an unfavorable environment can trigger short- and long-term stress, which causes irreversible harm [5]. Studies from many countries around the world have demonstrated the significant impact of neighborhood environmental characteristics – such as housing conditions, availability of green spaces, neighborhood social support, safety, and others – on residents’ mental health [9]. In 2002, Lawrence R.J. showed that insufficient safety, high noise levels, and limited access to amenities and green areas within the neighborhood was associated with mental well-being decline [12]. Numerous studies have further demonstrated that in neighborhoods lacking public amenities, safe environments, and adequate housing, residents experience elevated stress levels and an increased risk of depression [13]. These findings encourage researchers and urban planners to place greater emphasis on creating resident-oriented, comfortable living environments [3].

Studies have examined not only the overall level of neighborhood comfort but also the influence of specific components (characteristics). For instance, the beneficial effects of nature and urban greenery on mental health have been demonstrated in numerous studies conducted worldwide [9, 14, 15]. Other studies have highlighted the importance of crime rates, access to amenities, and neighborhood satisfaction in relation to physical health and several aspects of mental health, including stress, depression, and anxiety [16]. Perceived stress from traffic has been found to be primarily associated with general health status and depression, whereas neighborhood safety and residents’ social connections are more strongly related to mental health [16].

Most of these studies have focused predominantly on green spaces, while the influence of other important neighborhood characteristics – such as population density, the number and accessibility of infrastructure facilities, road safety, pedestrian infrastructure, and other resident-relevant parameters – on mental well-being has rarely been assessed. At the same time, successful development and implementation of preventive measures targeting environmental factors that affect mental health require an understanding of how differences in residential conditions across specific territories influence population health. Moreover, the vast majority of these studies have been conducted abroad, which limits the applicability of their findings to the Russian population. The few Russian studies available have mainly examined associations between neighborhood infrastructure and physical health indicators [17, 18, 19] or have not addressed the general population [20].

Therefore, the aim of the present study was to investigate the associations between neighborhood infrastructure characteristics and the individual probability of stress among Russian citizens.

 

Material and Methods

Data for this analysis were drawn from the Russian multicenter study Epidemiology of Cardiovascular Diseases and Their Risk Factors in Regions of the Russian Federation. Third Survey (ESSE-RF-3), conducted in 2020-2022 across 15 regions of the Russian Federation. The total sample included 28,731 men and women aged 35-74 years. Detailed information on the sampling procedures has been published previously [21]. The study was approved by the Ethics Committee of the National Medical Research Center for Therapy and Preventive Medicine and conducted in accordance with Good Clinical Practice (GCP) standards and the principles of the Declaration of Helsinki. All participants provided written informed consent.

Neighborhood infrastructure was assessed using the Russian-language version of the Neighborhood Environmental Walkability Scale (NEWS) [22]. Based on the questionnaire results, quantitative values were calculated for eight scales:

  • Higher values on Scale A indicated greater population density.
  • Higher values on Scale B indicated shorter average distances between facilities and the respondent’s place of residence.
  • Higher scores on Scales C through H indicated increased accessibility, walkability, quality, and safety of neighborhood infrastructure. Specifically, Scale C captured access to facilities; Scale D, street walkability; Scale E, quality of pedestrian infrastructure; Scale F, neighborhood aesthetics; Scale G, traffic-related safety; and Scale H, crime-related safety.

All scales had quantitative measures. The range of Scale A was 1-75; Scale B, 1-5; and Scales C-H, 1-4. The mean values ± standard deviation for the total sample were as follows: Scale A – 26.1±17.5, Scale B – 2.7±0.8, Scale C – 3.0±0.5, Scale D – 2.8±0.7, Scale E – 2.8±0.7, Scale F – 2.6±0.7, Scale G – 2.7±0.4, and Scale H – 3.3±0.7.

Stress levels were assessed using the Perceived Stress Scale (PSS), scored according to Cohen’s Stress Scale [23]. Scores in the upper quartile (≥18 points) were classified as indicative of stress.

Investigated associations were adjusted for a range of individual covariates: sex, age, place of residence (urban/rural), income, marital status (married / not married), educational attainment (higher education / no higher education), smoking, and physical activity level. Income was indirectly assessed using three questions capturing the proportion of income spent on food, respondents’ perceptions of their family’s financial resources, and their perceived standard of living relative to other families. Respondents’ occupations were grouped into “white-collar,” “blue-collar,” and “nonworking” categories based on self-reported professional categories, classified according to the International Labour Organization’s ISCO-08 standard. Overall physical activity was assessed using the Global Physical Activity Questionnaire (GPAQ), with metabolic equivalents (METs) calculated and adequate physical activity defined as >600 MET-minutes per week [24].

Associations between neighborhood infrastructure and stress were evaluated using logistic regression. All covariates were included in the models. Scores for Scales A–H were entered simultaneously. If a statistically significant association between a specific infrastructure scale and stress was identified, additional analyses were conducted to examine associations between stress and each item within that scale. In such cases, all items from the scale were entered simultaneously into the regression model, while other scales and covariates remained unchanged. Associations are presented as odds ratios (OR) with 95% confidence intervals (CI). Statistical analyses were performed using SPSS software, version 22 (IBM Corp., USA).

 

Results

In the study sample, men and women were equally represented. Most participants resided in urban areas, had a family, and were evenly distributed across age strata and education levels (Table 1). Nearly half of the respondents reported a middle income and were employed in non-industrial occupations. Only 27.4% had adequate physical activity, and 17% of the sample reported smoking. According to the methodology, every fourth participant (25.5%) had a high perceived stress score on the PSS scale.

 

Table 1. Sample characteristics.

Characteristic

Criteria

Percentage (n)

Men

 

47.0 (13,490)

 

Age

35-44

25.0 (7,189)

45-54

25.3 (7,268)

55-64

26.1 (7,501)

65-74

23.6 (6,773)

Urban residence

 

78.5 (22,563)

 

Income

Low

26.8 (7,699)

Middle

55.8 (16,026)

High

17.4 (5,006)

Higher education

 

47.0 (13,512)

Family

 

69.2 (19,874)

 

Occupation

White-collar

45.5 (13,075)

Blue-collar

19.6 (5,639)

Other

34.9 (10,017)

Adequate physical activity

 

27.4 (7,885)

Smoking

 

17.0 (4,879)

Stress

≥18 points

25.5 (7,322)

 

A regression analysis of the stress level in relation to neighborhood infrastructure is presented in Table 2. Findings of the additional analysis are provided in the Appendix. An increase in neighborhood population density (Scale A) was associated with a higher likelihood of stress (OR=1.002; 95% CI 1.001-1.004).

 

Table 2. Associations between infrastructure-related scales and stress

Infrastructure characteristic

Stress (n=28,426)

OR (95% CI)

p-value

Scale A: population density

1.002 (1.001-1.004)

0.016

Scale B: distance

0.91 (0.87-0.94)

<0.001

Scale C: accessibility

0.51 (0.48-0.55)

<0.001

Scale D: walkability

0.90 (0.85-0.94)

<0.001

Scale E: pedestrian infrastructure

1.16 (1.10-1.22)

<0.001

Scale F: aesthetics

1.08 (1.03-1.13)

0.001

Scale G: safety (traffic)

0.60 (0.56-0.66)

<0.001

Scale H: safety (crime)

1.05 (1.01-1.10)

0.021

Adjusted for sex, age, urban/rural residence, income, marital status, education, occupation, smoking, and physical activity.

 

Shorter distances from residence to infrastructure facilities (Scale B) were associated with a reduced likelihood of stress (OR=0.91; 95% CI 0.87–0.94).

Greater accessibility of key infrastructure facilities (Scale C) – such as shops, shopping centers, and public transport stops – as well as higher overall walkability of the neighborhood (Scale D) were both associated with lower odds of stress (OR=0.51; 95% CI 0.48-0.55 and OR=0.90; 95% CI 0.85-0.94, respectively).

Improved pedestrian infrastructure quality (Scale E) was positively associated with stress probability (OR=1.16; 95% CI 1.10-1.22). However, within this scale, only the the number of cars parked between the road and the sidewalk showed a significant association: the more parked cars, the higher the likelihood of stress (OR=1.17; 95% CI 1.12-1.22).

Higher aesthetic characteristics of the neighborhood (Scale F) were associated with an increased likelihood of stress (OR=1.08; 95% CI 1.03-1.13). This relationship was mainly mediated by the presence of interesting places to look at (OR=1.05; 95% CI 1.00-1.09). At the same time, the presence of greenery along the streets was inversely associated with stress probability (OR=0.94; 95% CI 0.90-0.98).

Greater traffic-related safety (Scale G) was associated with a reduced likelihood of stress (OR=0.60; 95% CI 0.56–0.66), primarily due to fewer cars, lower traffic speed near residential areas, and improved street lighting (Appendix).

An increase in the safety of the respondent's place of residence was associated with an increase in the likelihood of stress (OR=1.05; 95% CI 1.01-1.10), mainly due to daytime safety (Appendix).

 

Discussion

The findings of this study showed a significant, and at times ambiguous, impact of neighborhood environment and its specific components on the likelihood of stress among the Russian population. Higher population density in residential areas negatively influenced stress indicators, which is consistent with the majority of studies conducted worldwide. A study carried out in Guangzhou, China, reported that a one–percentage point increase in building density was associated with a 0.08-unit decrease in General Health Questionnaire (GHQ, a mental health measure) scores, whereas a one-unit increase in per capita green space was associated with a 0.18-unit decrease in GHQ [9]. The greater the number of buildings and enclosed spaces, the narrower the streets and roadways, and the fewer the green areas, water bodies, and sunlight, the higher the susceptibility to stress, the lower the emotional well-being, and the greater the overall deterioration in mental health [3, 25].

A more detailed analysis of our results revealed that the adverse effect of “pedestrian infrastructure” on stress levels was mediated by the presence of cars parked between the road and the sidewalk. The negative impact of parked cars on residents’ psycho-emotional state can be explained by narrow streets and sidewalks, additional difficulties when crossing roads, obstacles for pedestrians, and restricted visibility of walking areas, all of which create further discomfort.

To our surprise, Scale F, reflecting neighborhood aesthetics, was also negatively associated with stress levels. The strongest negative contribution came from residents’ agreement with the statement about the presence of “many interesting places to look at” in the neighborhood. This is likely related to the greater number of visitors to such areas, which can create additional inconveniences (domestic, economic, transport, and social) and negatively affect the health, safety, and well-being of residents. Similar findings were reported by Huang et al. (2021), who showed that cultural or historical sites, and recreational areas were significantly associated with an increased risk of depression [26].

Our study demonstrated that neighborhood safety decrease stress indicators. These findings stand in line with prior research, showing that an unfavorable environment, crime, antisocial behavior, vandalism, and neglected surroundings are predictors of mental health decline, that lead to stress and anxiety, sleep disturbances and other deteriorations in psychological well-being [4, 9, 27, 28]. When analysing neighborhood safety components, negative perceptions were primarily linked to “feeling unsafe when walking in the neighborhood during the day due to crime.” Adult residents, who may feel a personal responsibility for the safety of younger generations, could be particularly concerned, as children and grandchildren tend to spend more time in the area during daylight hours. Evidence suggests that individuals with sedentary lifestyles may attribute their inactivity to unfavorable neighborhood conditions, perceiving the area as unsafe [4]. Moreover, visible signs of a neighborhood disorder – such as graffiti, litter, and vandalism – common in many modern urban districts, can elicit negative emotions and heighten fear of crime, thereby contributing to increased stress and anxiety [27].

In our study, numerous neighborhood characteristics demonstrated a protective role in mitigating stress. As anticipated, shorter distances to key daily used infrastructure (e.g. supermarkets, post offices, schools, food outlets, fitness centres, laundries) were associated with lower stress levels. This observation indirectly supports the influence of accessibility (Scale C) of amenities (shops, parking slots, etc.) and the absence of mobility barriers in reducing the likelihood of stress. Khosravi and Tehrani (2019) likewise identified neighborhood safety and walkability as key determinants of mental health among older adults [28]. Furthermore, high walkability, together with access to public services and amenities, green spaces, and recreational areas, has consistently been shown to exert beneficial effects on mental health outcomes, enhancing quality of life and alleviating psychological stress [5, 9, 29].

As supported by our findings, perceived traffic safety in the residential environment may also play a role in reducing stress. When nearby traffic is slower, drivers comply with speed limits, vehicular flow does not impede pedestrian movement, and streets are adequately illuminated, residents are more likely to perceive local traffic as safe, which in turn exerts a favorable effect on stress indicators. These results are consistent with evidence from other countries. A systematic review of studies evaluating the impact of transport and traffic activity demonstrated that higher traffic volumes, road congestion, and the difficulty of crossing streets obstruct residents’ social interaction, thereby leading to poorer mental health outcomes [30, 31].

Thus, our study demonstrated that proximity and pedestrian accessibility of public facilities and services, together with high street walkability, perceived pedestrian safety, and favorable traffic conditions, represent important environmental determinants of mental health, contributing to a reduced likelihood of stress. In contrast, higher population density, lower safety indicators, inadequate pedestrian infrastructure, and the presence of tourist attractions within the neighborhood are associated with an increased likelihood of stress among residents.

 

Conclusion

This study provides important evidence on the influence of neighborhood conditions on the mental health of the Russian population.

Consistent with large-scale epidemiological studies worldwide, our findings showed the substantial impact of neighborhood environment on stress, a key indicator of population health. Critical factors include population density, distance to and well-designed pedestrian accessibility of neighborhood facilities, as well as perceived safety. All these factors shape neighborhood perception and may mediate the relationship between the residential environment and stress.

Overall, obtained results advance understanding of how specific neighborhood characteristics affect the population health and well-being. Associations between place of residence and mental health carry practical significance and implications for public health, government policy, and urban and district planning.

Investments in healthy neighborhood environment may improve human health across the lifespan, reduce health disparity, and enhance overall quality of life at the population level.

 

Ethical approval

The study was approved by the Ethics Committees of National Research Center for Therapy and Preventive Medicine (Moscow, Russian Federation) No. 01–01/20 (04.02.2020) and No. 04-08/20 (02.07.2020).

 

Conflict of interest

The authors declare that they have no conflict of interest.

 

Funding

This research did not receive any external funding.

 

AI statement

The authors declare that no generative AI or AI-assisted technologies were used in the preparation of this manuscript.

 

Appendix. Associations between neighborhood infrastructure characteristics and stress among the Russian population

 

Scale

Neighborhood infrastructure characteristics

Stress

OR (95% CI)

p-value

В

Small grocery store

1.19 (1.12-1.28)

<0.001

Supermarket

0.94 (0.89-0.99)

0.039

Hardware store

1.07 (1.00-1.13)

0.037

Fruit/vegetable market

0.97 (0.93-1.02)

0.29

Laundry/dry cleaner

0.90 (0.86-0.95)

<0.001

Clothing store

1.05 (0.99-1.11)

0.12

Post office

0.92 (0.87-0.97)

0.002

Library

0.96 (0.91-1.01)

0.085

Kindergarten

0.96 (0.90-1.03)

0.27

School

0.92 (0.86-0.98)

0.012

Bookstore

1.12 (1.06-1.18)

<0.001

Cafe/fast food outlet

1.03 (0.97-1.09)

0.30

Bank

0.99 (0.94-1.06)

0.95

Restaurant

0.95 (0.91-1.01)

0.078

Pharmacy

1.01 (0.95-1.07)

0.78

Hairdresser

1.01 (0.95-1.06)

0.78

Public transport stop

1.15 (1.09-1.21)

<0.001

Park

0.99 (0.94-1.04)

0.67

Cultural/entertainment centre

1.03 (0.97-1.09)

0.39

Gym

0.91 (0.86-0.96)

0.001

С

Shops are within walking distance from home

0.87 (0.84-0.91)

<0.001

Parking near nearby shops/shopping centres is difficult

0.89 (0.86-0.92)

<0.001

Many facilities are within walking distance of home

0.93 (0.89-0.97)

0.001

Bus stop is within walking distance of home

0.92 (0.88-0.96)

<0.001

Streets in my neighborhood are hilly, making walking difficult

0.88 (0.85-0.92)

<0.001

There are serious barriers to walking in the neighborhood

0.88 (0.85-0.92)

<0.001

D

Few cul-de-sacs in the neighborhood

0.95 (0.92-0.98)

0.001

Short distances between intersections in the neighborhood

0.98 (0.94-1.01)

0.22

Many alternative routes available nearby

0.97 (0.93-1.01)

0.16

E

Most streets have sidewalks

1.00 (0.95-1.04)

0.87

Cars parked between road and sidewalk

1.17 (1.12-1.22)

<0.001

Median strip between road and sidewalk

0.98 (0.95-1.02)

0.39

F

Trees line the streets in the neighborhood

0.94 (0.90-0.98)

0.002

Many interesting places to look at in the neighborhood

1.05 (1.00-1.09)

0.041

Many natural attractions in the neighborhood

1.03 (0.98-1.07)

0.22

Beautiful buildings in the neighborhood

1.03 (0.98-1.07)

0.20

G

So many cars on nearby streets that walking is difficult

0.87 (0.83-0.90)

<0.001

Cars on nearby streets usually travel slowly (≤50 km/h)

0.93 (0.90-0.97)

<0.001

Most drivers exceed speed limits in the neighborhood

0.87 (0.83-0.90)

<0.001

Neighborhood streets are well lit at night

0.90 (0.86-0.94)

<0.001

Many pedestrians on the streets in the neighborhood

0.98 (0.94-1.02)

0.37

Many pedestrian crossings and traffic lights in the neighborhood

0.97 (0.93-1.01)

0.19

H

High crime rate in the neighborhood

1.01 (0.96-1.08)

0.62

Daytime walks in the neighborhood are unsafe due to crime

1.08 (1.01-1.15)

0.019

Night-time walks in the neighborhood are unsafe due to crime

0.97 (0.91-1.02)

0.24

Adjusted for sex, age, urban/rural residence, income, family status, education, occupation, smoking, and physical activity.
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About the Authors: 

Marina B. Kotova – PhD, Leading Researcher, Laboratory of Geospatial And Environmental Factors of Health, Department of Epidemiology of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0002-6370-9426
Sergey A. Maksimov – MD, DSc, Associate Professors, Head of the Laboratory of Geospatial And Environmental Factors of Health, Department of Epidemiology of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0003-0545-2586.
Svetlana A. Shalnova – MD, DSc, Professor, Head of the Department of Epidemiology of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0003-2087-6483
Yulia A. Balanova – MD, DSc, Leading Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0001-8011-2798.
Asiia E. Imaeva – MD, DSc, Leading Researcher, Department of Epidemiology of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0002-9332-0622.
Vladimir A. Kutsenko – PhD, Senior Researcher, Department Of Epidemiology Of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0001-9844-3122.
Galina A. Muromtseva – PhD, Leading Researcher, Department Of Epidemiology Of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0002-0240-3941.
Svetlana E. Evstifeeva – MD, PhD, Senior Researcher, Department Of Epidemiology Of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0002-7486-4667.
Anna V. Kapustina – Senior Researcher, Department Of Epidemiology Of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0002-9624-9374.
Natalia S. Karamnova – MD, DSc, Head of the Nutrition Epidemiology Laboratory, Department Of Epidemiology Of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0002-8604-712X.
Olga B. Shvabskaya – Researcher, Nutrition Epidemiology Laboratory, Department Of Epidemiology Of Chronic Non-Communicable Diseases, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0001-9786-4144.
Tatyana V. Repkina – MD, PhD, Chief Physician, Regional Center for Public Health and Medical Prevention, Barnaul, Russia. https://orcid.org/0000-0003-4583-313X.
Tatyana O. Gonoshilova – Head of the Department for Monitoring Risk Factors for Noncommunicable Diseases, Regional Center for Public Health and Medical Prevention, Barnaul, Russia. https://orcid.org/0000-0002-7522-9286.
Alexander V. Kudryavtsev – PhD, Associate Professors, Head of International Research Competence Centre, Central Scientific Research Laboratory, Northern State Medical University, Arkhangelsk, Russia. https://orcid.org/0000-0001-8902-8947.
Natalia I. Belova – Junior Researcher, Central Scientific Research Laboratory, Northern State Medical University, Arkhangelsk, Russia. https://orcid.org/0000-0001-9066-5687.
Leonid L. Shagrov – Junior Researcher, Central Scientific Research Laboratory, Northern State Medical University, Arkhangelsk, Russia. https://orcid.org/0000-0003-2655-9649.
Marina A. Samotrueva – MD, DSc, Professor, Head of the Department of Pharmacognosy, Pharmaceutical Technology and Biotechnology, Astrakhan State Medical University, Astrakhan, Russia. https://orcid.org/0000-0001-5336-4455.
Anna L. Yasenyavskaya – MD, PhD, Associate Professor, Head of the Research Center, Associate Professor, Department of Pharmacognosy, Pharmaceutical Technology and Biotechnology, Astrakhan State Medical University, Astrakhan, Russia. https://orcid.org/0000-0003-2998-2864.
Olga A. Bashkina – MD, DSc, Professor, Head of the Faculty of Paediatrics, Astrakhan State Medical University, Astrakhan, Russia. https://orcid.org/0000-0003-4168-4851.
Svetlana V. Glukhovskaya – Head of Preventive Projects of the Development Department, Sverdlovsk Regional Medical College, Ekaterinburg, Russia. https://orcid.org/0000-0002-1534-6587.
Irina A. Levina – Director, Sverdlovsk Regional Medical College, Ekaterinburg, Russia. https://orcid.org/0000-0002-1359-0703.
Ekaterina A. Shirshova – MD, PhD, Head of the Public Health Center for Youth, Sverdlovsk Regional Medical College, Ekaterinburg, Russia. https://orcid.org/0009-0004-9077-5949.
Etta B. Dorzhieva – Chief Physician, Boyanov Center for Public Health and Medical Prevention, Ulan-Ude, Russia. https://orcid.org/0009-0002-3744-3481.
Ekaterina Z. Urbanova – MD, PhD, Head of the Risk Factor Monitoring Department, Boyanov Center for Public Health and Medical Prevention, Ulan-Ude, Russia. https://orcid.org/0009-0003-2784-0894.
Natalia Yu. Borovkova – MD, DSc, Associate Professor, Department of Hospital Therapy and General Medical Practice named after V.G. Vogralik, Privolzhsky Research Medical University, Nizhny Novgorod, Russia. https://orcid.org/0000-0001-7581-4138.
Vladimir K Kurashin – Assistant, Department of Hospital Therapy and General Medical Practice named after V.G. Vogralik, Privolzhsky Research Medical University, Nizhny Novgorod, Russia. https://orcid.org/0000-0002-3730-5831.
Anastasia S. Tokareva – Assistant, Department of Hospital Therapy and General Medical Practice named after V.G. Vogralik, Privolzhsky Research Medical University, Nizhny Novgorod, Russia. https://orcid.org/0000-0003-0640-6848.
Yulia I. Ragino – MD, DSc, Professor, Corresponding Member of the Russian Academy of Sciences, Head, Research Institute of Internal and Preventive Medicine – branch of the Institute of Cytology and Genetics, Novosibirsk, Russia. https://orcid.org/0000-0002-4936-8362.
Galina I. Simonova – MD, DSc, Professor, Chief Researcher of the Laboratory of Etiopathogenesis and the Clinic of Internal Diseases, Research Institute of Internal and Preventive Medicine – branch of the Institute of Cytology and Genetics, Novosibirsk, Russia. https://orcid.org/0000-0002-4030-6130.
Alyona D. Khudyakova – MD, PhD, Head of the Laboratory of Genetic and Environmental Determinants of the Human life cycle, Research Institute of Internal and Preventive Medicine – branch of the Institute of Cytology and Genetics, Novosibirsk, Russia. https://orcid.org/0000-0001-7875-1566.
Vadim N. Nikulin – MD, PhD, Chief Physician, Orenburg Regional Center for Public Health and Medical Prevention, Orenburg, Russia. https://orcid.org/0000-0001-6012-9840.
Oleg R. Aslyamov – Deputy Chief Physician for Organizational Work, Orenburg Regional Center for Public Health and Medical Prevention, Orenburg, Russia. https://orcid.org/0009-0004-6488-1465.
Galina V. Khokhlova – Head of the Department of Health Monitoring and Risk Factors, Orenburg Regional Center for Public Health and Medical Prevention, Orenburg, Russia. https://orcid.org/0009-0007-4585-1190.
Alla V. Solovieva – MD, PhD, Associate Professors, Vice-Rector for the Implementation of National Projects and the Development of Regional Healthcare, Head of the Department of Medical Information Technology and Healthcare Organization, Tver State Medical University, Tver, Russia. https://orcid.org/0000-0002-7675-6889.
Andrey A. Rodionov – MD, PhD, Associate Professor, Department of Medical Information Technology and Healthcare Organization, Tver State Medical University, Tver, Russia. https://orcid.org/0000-0002-7226-772X.
Olga V. Kryachkova – Senior Lecturer, Department of Medical Information Technology and Healthcare Organization, Tver State Medical University, Tver, Russia. https://orcid.org/0000-0001-7535-221Х.
Yulia Yu. Shamurova – MD, DSc, Associate Professor, Head of the Department of Outpatient Therapy and Clinical Pharmacology, South Ural State Medical University, Chelyabinsk, Russia. https://orcid.org/0000-0001-8108-4039.
Evgeny V. Mikhailov – MD, PhD, Associate Professor, Department of Polyclinic Therapy and Clinical Pharmacology, South Ural State Medical University, Chelyabinsk, Russia. https://orcid.org/0009-0003-3554-8914
Yulia O. Tarabrina – MD, PhD, Associate Professor, Department of Polyclinic Therapy and Clinical Pharmacology, South Ural State Medical University, Chelyabinsk, Russia. https://orcid.org/0009-0007-4014-4091.
Magomedrasul G. Ataev – MD, PhD, Associate Professor, Department of Clinical Pharmacology, Abusuev Research Institute of Environmental Medicine, Dagestan State Medical University, Makhachkala, Russia. https://orcid.org/0000-0001-9073-0119.
Magomed O. Radzhabov – MD, PhD, Associate Professor, Head of Genomic Research at the Institute of Physics, Dagestan Federal Research Centre of the Russian Academy of Sciences, Makhachkala, Russia. https://orcid.org/0000-0002-8339-2577.
Zulmira M. Gasanova – Assistant, Department of General Hygiene and Human Ecology, Abusuev Research Institute of Environmental Medicine, Dagestan State Medical University, Makhachkala, Russia. https://orcid.org/0009-0002-0106-4957.
Murat A. Umetov – MD, DSc, Professor, Head of the Department of Faculty Therapy, Berbekov Kabardino-Balkarian State University, Nalchik, Russia. https://orcid.org/0000-0001-6575-3159.
Inara A. Hakuasheva – Assistant, Department of Faculty Therapy, Berbekov Kabardino-Balkarian State University, Nalchik, Russia. https://orcid.org/0000-0003-2621-0068.
Lilia V. Elgarova – MD, DSc, Associate Professor, Head of the Department of Propaedeutics of Internal Diseases, Berbekov Kabardino-Balkarian State University, Nalchik, Russia. https://orcid.org/0000-0002-7149-7830.
Ekaterina I. Yamashkina – MD, PhD, Associate Professor, Department of Dietetics, Endocrinology, Hygiene with a course in Neonatology, Ogarev Mordovian State University, Saransk, Russia. https://orcid.org/0009-0004-5092-7872.
Larisa A. Balykova – MD, DSc, Professor, Director of the Medical institute, Ogarev Mordovia State University, Ogarev Mordovian State University, Saransk, Russia. https://orcid.org/0000-0002-2290-0013.
Anna A. Usanova – MD, DSc, Professor, Head of the Department of Faculty Therapy with a Course of Medical Rehabilitation, Ogarev Mordovia State University, Ogarev Mordovian State University, Saransk, Russia. https://orcid.org/0000-0003-2948-4865.
Alyona M. Nikitina – Head Physician, Republican Center for Public Health and Medical Prevention, Yakutsk, Russia. https://orcid.org/0000-0001-9149-1359.
Nadezhda V. Savvina – MD, DSc, Professor, Head of the Department of Healthcare Organization and Preventive Medicine, Ammosov North-Eastern Federal University, Yakutsk, Russia. https://orcid.org/0000-0003-2441-6193.
Yulia E. Spiridonova – Head of the Project Development and Implementation Department, Ammosov North-Eastern Federal University, Yakutsk, Russia. https://orcid.org/0009-0004-1205-4767.
Elena A. Naumova – Deputy Chief Physician for Medical Prevention, Republican Center for Public Health and Medical Prevention, Exercise Therapy and Sports Medicine, Cheboksary, Russia. https://orcid.org/0000-0003-3574-2111.
Daria A. Kashtanova – MD, PhD, Lead Analyst, Medical Genomics Department, Center for Strategic Planning and Management of Biomedical Health Risks, Moscow, Russia. https://orcid.org/0000-0001-8977-4384.
Vladimir S. Yudin – PhD, Head of the Medical Genomics Department, Center for Strategic Planning and Management of Biomedical Health Risks, Moscow, Russia. https://orcid.org/0000-0002-9199-6258.
Anton A. Keskinov – PhD, Head of the Department for the Organization of Scientific Research, Center for Strategic Planning and Management of Biomedical Health Risks, Moscow, Russia. https://orcid.org/0000-0001-7378-983X.
Sergey M. Yudin – MD, DSc, Professor, General Director, Center for Strategic Planning and Management of Biomedical Health Risks, Moscow, Russia. https://orcid.org/0000-0002-7942-8004.
Anna V. Kontsevaya – MD, DSc, Deputy director on science and analytics, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0003-2062-1536.
Oxana M. Drapkina – MD, DSc, Professor, Academician of the Russian Academy of Sciences, Director, National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia. https://orcid.org/0000-0002-4453-8430

Received 13 May 2025, Revised 20 June 2025, Accepted 14 July 2025
© 2025, Russian Open Medical Journal 
Correspondence to Marina B Kotova. Phone: +79161379822. E-mail: mkotova@gnicpm.ru.